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MAST HÜCRESİ


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Medicine and Hematology Glossary

MAST HÜCRESİ

(Medicine and Hematology Glossary) :
Morfolojık olarak bazofillere benzerlikleri olmakla beraber bazofillerden farklı hücrelerdir. Sitoplazmalarında çekirdeği örtecek derecede koyu mavi granülleri vardır. Normal periferik kanda mast hücresi görülmez. Çok az olarak kemik iliğinde görülür. Konnektif doku ve seröz boşluklarda bulunurlar. Mast hücresi granülleri bazofile göre daha küçük ve daha çok sayıdadır. Membranda IgE reseptörü bulunur ve bu reseptörün IgE ile bağlanması anaflaksi yapan hücre granüllerinin boşalmasına neden olur. Histamin sentezler ve depolar.
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